I'm ready to throw the towel in on this 20 year friendship! What to do?

Sorry this is so long I am so frustrated.I open my home to my friend and her 2 children and 1 grandchild. Its been a nightmare for 2 months. She barely cleans up she has a trash bag in the room with dirty diapers and food. She crammed almost 2 rooms into 1 you can hardly walk in it. Things are braking getting ruined. She burned up a pot on the stove the smoke detector went off so it was really bad. I'm in my room she didn't say nothing when I said what happened. Later that night she said it was an accident wow 8 hours later she wants to say something. One of the kids breaks a drinking glass so I said why you didn't pick all the broken glass up she says that they didn't do it that she thought that I did. I asked her if she thought I was stupid or something glass breaking sounds different on carpet than on tile. She said that the children were in the room that was a lie because the glass broke in the kitchen. One of them was in the kitchen. They pick some up from the floor. So now I want them to move I have had all I can take this situation is not working for me. She has lived with other people and I think that some of them asked her to leave. I giving her one more month she has been here 2 months and it is driving me up the wall. She is very irresponsible. Sometimes I'm afraid to go to work because of what might happen to my home. So now she is playing the friends card.She said that we have been friends to long for things to be like this. She is one of those friends that you don't want to be around to long because you will get a headache. She is a user and a liar. When I'm with my other friends or boyfriend she gets mad. She tells me she doesn't like my friends. i have never told her that I don't like any of her friends. People have told me a long time ago that I should cut her loose. We really have not talked since she moved in. Am I being a grouch. Another thing is that a few years back she wanted me to ride with her somewhere she says put on some nice clothes I'm thinking we are going to brunch or something we rode around for about 20 minutes we stopped in front of a funeral home she wanted me to go to a funeral with her wtf. What do you think about this situation? What kind of friend would you say she is? Thanks in advance.